| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 21st, 2008 | 32 | No |
6-Methyl-1,11-dioxy-2-naphthacenecarboxamide
Achromycin (naphthacene derivative)
Achromycin, naphthacene derivative
methyl-1,11-dioxo-2-naphthacenecarboxamide
Tetracycline Monohydrochloride
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.69 | -0.66 | -51.3 | 7 | 10 | 0 | 186 | 444.44 | 2 | ↓ |
| Hi High (pH 8-9.5) | -0.69 | -1.62 | -108.63 | 5 | 10 | -2 | 187 | 442.424 | 2 | ↓ |
| Hi High (pH 8-9.5) | -1.27 | -0.27 | -25.12 | 5 | 10 | 0 | 181 | 443.432 | 2 | ↓ |
| Hi High (pH 8-9.5) | -1.27 | 2.42 | -74.7 | 5 | 10 | 0 | 185 | 443.432 | 2 | ↓ |
| Hi High (pH 8-9.5) | -1.27 | 0.73 | -98.26 | 4 | 10 | 0 | 184 | 442.424 | 2 | ↓ |
| Hi High (pH 8-9.5) | -0.24 | -0.44 | -236.61 | 4 | 10 | -3 | 190 | 441.416 | 2 | ↓ |
| Hi High (pH 8-9.5) | -0.24 | -1.43 | -134.78 | 5 | 10 | -2 | 187 | 442.424 | 2 | ↓ |
| Hi High (pH 8-9.5) | -0.69 | 1.38 | -166.11 | 5 | 10 | -2 | 191 | 442.424 | 2 | ↓ |
| Mid Mid (pH 6-8) | -0.24 | 0.76 | -113.53 | 6 | 10 | -1 | 188 | 443.432 | 2 | ↓ |
| Mid Mid (pH 6-8) | -1.27 | 1.43 | -58.35 | 6 | 10 | 0 | 182 | 444.44 | 2 | ↓ |
| Mid Mid (pH 6-8) | -0.69 | -2.61 | -55 | 6 | 10 | -1 | 184 | 443.432 | 2 | ↓ |
| Lo Low (pH 4.5-6) | -1.42 | -2.2 | -50.63 | 8 | 10 | 1 | 183 | 445.448 | 1 | ↓ |
| Lo Low (pH 4.5-6) | -1.27 | -1.21 | -39.35 | 7 | 10 | 0 | 180 | 445.448 | 2 | ↓ |
| Lo Low (pH 4.5-6) | -1.42 | -2.93 | -19.11 | 7 | 10 | 0 | 182 | 444.44 | 1 | ↓ |
No pre-computed analogs available. Try a structural similarity search.