| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 23rd, 2004 | 21 | Yes |
Popular Name: 2-(2-Propylpyridin-4-yl)-4-(p-tolyl)thiazole hydrobromide 2-(2-Propylpyridin-4-yl)-4-(p-to…
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CAS Number: 125256-00-0
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.13 | 10.19 | -6.91 | 0 | 2 | 0 | 26 | 294.423 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SRBP2-1-E | Sterol Regulatory Element-binding Protein 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 5600 | 0.35 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SRBP2_HUMAN | Q12772 | Sterol Regulatory Element-binding Protein 2, Human | 10000 | 0.33 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of gene expression by SREBF (SREBP) | |
| PPARA activates gene expression | |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | |
| Transcriptional regulation of white adipocyte differentiation |
