| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 23 | No |
Popular Name: 2-(3,5-ditert-butyl-4-hydroxy-benzylidene)cyclopent-4-ene-1,3-quinone 2-(3,5-ditert-butyl-4-hydroxy-be…
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| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.83 | 9.21 | -7.76 | 1 | 3 | 0 | 54 | 312.409 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EF2K-2-E | Serine/threonine-protein Kinase EEF2K (cluster #2 Of 2), Eukaryotic | Eukaryotes | 3200 | 0.33 | Binding ≤ 10μM |
| SRC-1-E | Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic | Eukaryotes | 2200 | 0.34 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EF2K_HUMAN | O00418 | Serine/threonine-protein Kinase EEF2K, Human | 3200 | 0.33 | Binding ≤ 10μM |
| SRC_HUMAN | P12931 | Tyrosine-protein Kinase SRC, Human | 2200 | 0.34 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| S6K1 signalling | |
| Signaling by ERBB2 |
