| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 24th, 2004 | 24 | Yes |
Popular Name: (2S,3S)-2-[[(2R)-1-[(2S,3S)-2-ammonio-3-methyl-pentanoyl]prolyl]amino]-3-methyl-valerate (2S,3S)-2-[[(2R)-1-[(2S,3S)-2-am…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.95 | -2.44 | -76.63 | 4 | 7 | 0 | 117 | 341.452 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TPP2-1-E | Tripeptidyl Aminopeptidase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.35 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TPP2_RAT | Q64560 | Tripeptidyl Aminopeptidase, Rat | 1000 | 0.35 | Binding ≤ 1μM |
| TPP2_RAT | Q64560 | Tripeptidyl Aminopeptidase, Rat | 1000 | 0.35 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Antigen processing: Ubiquitination & Proteasome degradation |
