| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 27th, 2004 | 14 | Yes |
Popular Name: (S)-4-carboxyphenylglycine (S)-4-carboxyphenylglycine
Find On: PubMed — Wikipedia — Google
CAS Number: 134052-73-6
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.42 | 3.83 | -80.65 | 3 | 5 | -1 | 108 | 194.166 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM1-1-E | Metabotropic Glutamate Receptor 1 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 3700 | 0.54 | Binding ≤ 10μM |
| XCT-2-E | Cystine/glutamate Transporter (cluster #2 Of 2), Eukaryotic | Eukaryotes | 5000 | 0.53 | Binding ≤ 10μM |
| GRM1-4-E | Metabotropic Glutamate Receptor 1 (cluster #4 Of 5), Eukaryotic | Eukaryotes | 10000 | 0.50 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| XCT_HUMAN | Q9UPY5 | Cystine/glutamate Transporter, Human | 5000 | 0.53 | Binding ≤ 10μM |
| GRM1_HUMAN | Q13255 | Metabotropic Glutamate Receptor 1, Human | 3700 | 0.54 | Binding ≤ 10μM |
| GRM1_HUMAN | Q13255 | Metabotropic Glutamate Receptor 1, Human | 10000 | 0.50 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Amino acid transport across the plasma membrane | |
| Basigin interactions | |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (q) signalling events |
