| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 3rd, 2009 | 34 | Yes |
Popular Name: CHEBI:378548 CHEBI:378548
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -4.40 | -8.96 | -75.52 | 8 | 15 | -1 | 250 | 491.474 | 12 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| UniProt Database Links | MGDP1_HUMAN; MGDP1_MOUSE; NALP1_HUMAN; NOD2_BOVIN; NOD2_HUMAN; NOD2_HYLLA; NOD2_MOUSE; NOD2_PANTR | ChEBI |
| Reactome Database Links | REACT_21338; REACT_21367; REACT_6935; REACT_75789; REACT_75796; REACT_75833; REACT_75843; REACT_75872; REACT_75873; REACT_75887; REACT_75888; REACT_75893; REACT_75903; REACT_75924 | ChEBI |
| Description | Species |
|---|---|
| activated TAK1 mediates p38 MAPK activation | |
| Interleukin-1 signaling | |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human | |
| NOD1/2 Signaling Pathway | |
| TAK1 activates NFkB by phosphorylation and activation of IKKs complex | |
| The NLRP1 inflammasome |
