| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 3rd, 2009 | 11 | Yes |
Popular Name: 1,2,3-Cyclopentanetriol, 4-amino-5-methoxy-, (1R,2R,3R,4S,5R)- (9CI) 1,2,3-Cyclopentanetriol, 4-amino…
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CAS Number: 288088-59-5
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -2.93 | -7.33 | -39.92 | 6 | 5 | 1 | 98 | 164.181 | 1 | ↓ |
| Hi High (pH 8-9.5) | -2.93 | -7.71 | -9.53 | 5 | 5 | 0 | 96 | 163.173 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MA1B1-1-E | Endoplasmic Reticulum Mannosyl-oligosaccharide 1,2-alpha-mannosidase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 160 | 0.86 | Binding ≤ 10μM |
| MA2A1-1-E | Alpha-mannosidase 2A1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 160 | 0.86 | Binding ≤ 10μM |
| MA2A2-1-E | Alpha-mannosidase 2A2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 160 | 0.86 | Binding ≤ 10μM |
| MA2B1-1-E | Lysosomal Alpha-mannosidase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 160 | 0.86 | Binding ≤ 10μM |
| MA2B2-1-E | Epididymis-specific Alpha-mannosidase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 160 | 0.86 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MA2A1_HUMAN | Q16706 | Alpha-mannosidase 2A1, Human | 160 | 0.86 | Binding ≤ 1μM |
| MA2A2_HUMAN | P49641 | Alpha-mannosidase 2A2, Human | 160 | 0.86 | Binding ≤ 1μM |
| MA1B1_HUMAN | Q9UKM7 | Endoplasmic Reticulum Mannosyl-oligosaccharide 1,2-alpha-mannosidase, Human | 160 | 0.86 | Binding ≤ 1μM |
| MA2B2_HUMAN | Q9Y2E5 | Epididymis-specific Alpha-mannosidase, Human | 160 | 0.86 | Binding ≤ 1μM |
| MA2B1_HUMAN | O00754 | Lysosomal Alpha-mannosidase, Human | 160 | 0.86 | Binding ≤ 1μM |
| MA2A1_HUMAN | Q16706 | Alpha-mannosidase 2A1, Human | 160 | 0.86 | Binding ≤ 10μM |
| MA2A2_HUMAN | P49641 | Alpha-mannosidase 2A2, Human | 160 | 0.86 | Binding ≤ 10μM |
| MA1B1_HUMAN | Q9UKM7 | Endoplasmic Reticulum Mannosyl-oligosaccharide 1,2-alpha-mannosidase, Human | 160 | 0.86 | Binding ≤ 10μM |
| MA2B2_HUMAN | Q9Y2E5 | Epididymis-specific Alpha-mannosidase, Human | 160 | 0.86 | Binding ≤ 10μM |
| MA2B1_HUMAN | O00754 | Lysosomal Alpha-mannosidase, Human | 160 | 0.86 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| ER Quality Control Compartment (ERQC) | |
| Reactions specific to the complex N-glycan synthesis pathway |
No pre-computed analogs available. Try a structural similarity search.