In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 25th, 2005 | 14 | Yes |
Popular Name: chloroBLAH chloroBLAH
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 1.97 | -2.65 | -46.06 | 2 | 2 | 1 | 19 | 209.7 | 0 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
5HT2A-1-E | Serotonin 2a (5-HT2a) Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 32 | 0.75 | Binding ≤ 10μM |
5HT2B-1-E | Serotonin 2b (5-HT2b) Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 53 | 0.73 | Binding ≤ 10μM |
5HT2C-1-E | Serotonin 2c (5-HT2c) Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 31 | 0.75 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
5HT2A_HUMAN | P28223 | Serotonin 2a (5-HT2a) Receptor, Human | 32 | 0.75 | Binding ≤ 1μM |
5HT2B_HUMAN | P41595 | Serotonin 2b (5-HT2b) Receptor, Human | 53 | 0.73 | Binding ≤ 1μM |
5HT2C_HUMAN | P28335 | Serotonin 2c (5-HT2c) Receptor, Human | 31 | 0.75 | Binding ≤ 1μM |
5HT2A_HUMAN | P28223 | Serotonin 2a (5-HT2a) Receptor, Human | 32 | 0.75 | Binding ≤ 10μM |
5HT2B_HUMAN | P41595 | Serotonin 2b (5-HT2b) Receptor, Human | 53 | 0.73 | Binding ≤ 10μM |
5HT2C_HUMAN | P28335 | Serotonin 2c (5-HT2c) Receptor, Human | 31 | 0.75 | Binding ≤ 10μM |
Description | Species |
---|---|
G alpha (q) signalling events | |
Serotonin receptors |