| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 6th, 2009 | 20 | Yes |
Popular Name: NS8593hydrochloride NS8593hydrochloride
Find On: PubMed — Wikipedia — Google
CAS Number: 875755-24-1
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.97 | 9.96 | -26.48 | 3 | 3 | 1 | 42 | 264.352 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNN3-1-E | Small Conductance Calcium-activated Potassium Channel Protein 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 130 | 0.48 | Binding ≤ 10μM |
| KCNN3-1-E | Small Conductance Calcium-activated Potassium Channel Protein 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 400 | 0.45 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNN3_HUMAN | Q9UGI6 | Small Conductance Calcium-activated Potassium Channel Protein 3, Human | 100 | 0.49 | Binding ≤ 1μM |
| KCNN3_RAT | P70605 | Small Conductance Calcium-activated Potassium Channel Protein 3, Rat | 130 | 0.48 | Binding ≤ 1μM |
| KCNN3_HUMAN | Q9UGI6 | Small Conductance Calcium-activated Potassium Channel Protein 3, Human | 100 | 0.49 | Binding ≤ 10μM |
| KCNN3_RAT | P70605 | Small Conductance Calcium-activated Potassium Channel Protein 3, Rat | 130 | 0.48 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Ca2+ activated K+ channels |
No pre-computed analogs available. Try a structural similarity search.