| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 8th, 2009 | 36 | Yes |
Popular Name: (3S)-1-(5-aminopentyl)-4-benzoyl-3-(1H-indol-3-ylmethyl)-3,5-dihydro-1,4-benzodiazepin-2-one (3S)-1-(5-aminopentyl)-4-benzoyl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.33 | 11.95 | -64.67 | 4 | 6 | 1 | 84 | 481.62 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SSR1-1-E | Somatostatin Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8200 | 0.20 | Binding ≤ 10μM |
| SSR2-1-E | Somatostatin Receptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8200 | 0.20 | Binding ≤ 10μM |
| SSR4-1-E | Somatostatin Receptor 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8200 | 0.20 | Binding ≤ 10μM |
| SSR5-1-E | Somatostatin Receptor 5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8200 | 0.20 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SSR1_RAT | P28646 | Somatostatin Receptor 1, Rat | 6500 | 0.20 | Binding ≤ 10μM |
| SSR2_RAT | P30680 | Somatostatin Receptor 2, Rat | 6500 | 0.20 | Binding ≤ 10μM |
| SSR4_RAT | P30937 | Somatostatin Receptor 4, Rat | 6500 | 0.20 | Binding ≤ 10μM |
| SSR5_RAT | P30938 | Somatostatin Receptor 5, Rat | 6500 | 0.20 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Peptide ligand-binding receptors |
