UCSF

ZINC26732206

Substance Information

In ZINC since Heavy atoms Benign functionality
February 9th, 2009 25 Yes

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.99 0.81 -54.25 6 7 1 124 345.375 7
Hi High (pH 8-9.5) 0.99 0.48 -20.67 5 7 0 122 344.367 7

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
SYYC-1-E Tyrosyl-tRNA Synthetase (cluster #1 Of 1), Eukaryotic Eukaryotes 1200 0.33 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
SYYC_HUMAN P54577 Tyrosyl-tRNA Synthetase, Human 1200 0.33 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Cytosolic tRNA aminoacylation

Analogs ( Draw Identity 99% 90% 80% 70% )