| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 12th, 2009 | 25 | Yes |
Popular Name: 3-ethyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-7-yl]-2-oxo-benzimidazole-1-carboxamide 3-ethyl-N-[(1R,5S)-9-methyl-9-az…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.54 | 9.97 | -38.46 | 2 | 6 | 1 | 60 | 343.451 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| 5HT4R-1-E | Serotonin 4 (5-HT4) Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 360 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| 5HT4R_MOUSE | P97288 | Serotonin 4 (5-HT4) Receptor, Mouse | 360 | 0.36 | Binding ≤ 1μM |
| 5HT4R_MOUSE | P97288 | Serotonin 4 (5-HT4) Receptor, Mouse | 360 | 0.36 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (s) signalling events | |
| Serotonin receptors |
