| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 15th, 2009 | 19 | Yes |
Popular Name: N-[[(1R,2S)-2-(2-methoxyphenyl)cyclopropyl]methyl]-N-propyl-propan-1-amine N-[[(1R,2S)-2-(2-methoxyphenyl)c…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.31 | 10.5 | -34.89 | 1 | 2 | 1 | 14 | 262.417 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| 5HT5A-1-E | Serotonin 5a (5-HT5a) Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 998 | 0.44 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| 5HT5A_RAT | P35364 | Serotonin 5a (5-HT5a) Receptor, Rat | 998 | 0.44 | Binding ≤ 1μM |
| 5HT5A_RAT | P35364 | Serotonin 5a (5-HT5a) Receptor, Rat | 998 | 0.44 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Serotonin receptors |
