| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 15th, 2009 | 19 | Yes |
Popular Name: (2S)-2-[[(2S,3S)-3-amino-2-hydroxy-5-methyl-hexanoyl]amino]-4-methyl-pentanoic (2S)-2-[[(2S,3S)-3-amino-2-hydro…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.28 | 2.83 | -68.54 | 5 | 6 | 0 | 117 | 274.361 | 8 | ↓ |
| Hi High (pH 8-9.5) | -1.28 | 2.52 | -57.14 | 4 | 6 | -1 | 115 | 273.353 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AMPL-1-E | Leucine Aminopeptidase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 120 | 0.51 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AMPL_HUMAN | P28838 | Leucine Aminopeptidase, Human | 120 | 0.51 | Binding ≤ 1μM |
| AMPL_HUMAN | P28838 | Leucine Aminopeptidase, Human | 120 | 0.51 | Binding ≤ 10μM |
