| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 19th, 2009 | 37 | Yes |
Popular Name: 1-[3-(1-methyl-4-piperidyl)propyl]-2-(phenoxymethyl)-4-[3-(1-piperidyl)propoxy]benzimidazole 1-[3-(1-methyl-4-piperidyl)propy…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.00 | 17.99 | -85.69 | 2 | 6 | 2 | 45 | 506.735 | 12 | ↓ |
| Lo Low (pH 4.5-6) | 6.00 | 18.4 | -140.23 | 3 | 6 | 3 | 46 | 507.743 | 12 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NPY1R-1-E | Neuropeptide Y Receptor Type 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2 | 0.33 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NPY1R_HUMAN | P25929 | Neuropeptide Y Receptor Type 1, Human | 1.62 | 0.33 | Binding ≤ 1μM |
| NPY1R_HUMAN | P25929 | Neuropeptide Y Receptor Type 1, Human | 1.62 | 0.33 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Peptide ligand-binding receptors |
