| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 19th, 2009 | 19 | Yes |
Popular Name: (2R)-2-[[(2S)-2-amino-3-methyl-butanoyl]amino]-N-butyl-pentanamide (2R)-2-[[(2S)-2-amino-3-methyl-b…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.37 | 2.72 | -44.11 | 5 | 5 | 1 | 86 | 272.413 | 9 | ↓ |
| Hi High (pH 8-9.5) | 1.37 | 2.39 | -9.68 | 4 | 5 | 0 | 84 | 271.405 | 9 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TPP2-1-E | Tripeptidyl Aminopeptidase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3000 | 0.41 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TPP2_RAT | Q64560 | Tripeptidyl Aminopeptidase, Rat | 3000 | 0.41 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Antigen processing: Ubiquitination & Proteasome degradation |
