In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
February 24th, 2009 | 32 | No |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 4.93 | 12.16 | -61.81 | 0 | 6 | -1 | 85 | 449.866 | 7 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
EDNRA-1-E | Endothelin Receptor ET-A (cluster #1 Of 3), Eukaryotic | Eukaryotes | 110 | 0.30 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
EDNRA_RAT | P26684 | Endothelin Receptor ET-A, Rat | 110 | 0.30 | Binding ≤ 1μM |
EDNRA_RAT | P26684 | Endothelin Receptor ET-A, Rat | 110 | 0.30 | Binding ≤ 10μM |
Description | Species |
---|---|
G alpha (q) signalling events | |
Peptide ligand-binding receptors |