| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 24th, 2009 | 29 | Yes |
Popular Name: N-[4-[(3R)-3-dimethylaminopyrrolidin-1-yl]phenyl]-6-(1-piperidyl)pyridine-3-carboxamide N-[4-[(3R)-3-dimethylaminopyrrol…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.20 | 8.75 | -42.25 | 2 | 6 | 1 | 53 | 394.543 | 5 | ↓ |
| Hi High (pH 8-9.5) | 3.20 | 6.31 | -10.84 | 1 | 6 | 0 | 52 | 393.535 | 5 | ↓ |
| Mid Mid (pH 6-8) | 3.20 | 9.03 | -84.42 | 3 | 6 | 2 | 54 | 395.551 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MCHR1-1-E | Melanin-concentrating Hormone Receptor 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2400 | 0.27 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MCHR1_HUMAN | Q99705 | Melanin-concentrating Hormone Receptor 1, Human | 2400 | 0.27 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| G alpha (q) signalling events | |
| Peptide ligand-binding receptors |
