| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 24th, 2009 | 25 | Yes |
Popular Name: 5-chloro-N-[2-(methyl-(4-pyridylmethyl)amino)-2-oxo-ethyl]-1H-indole-2-carboxamide 5-chloro-N-[2-(methyl-(4-pyridyl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.71 | 5.95 | -13.87 | 2 | 6 | 0 | 78 | 356.813 | 5 | ↓ |
| Lo Low (pH 4.5-6) | 1.71 | 6.38 | -45.65 | 3 | 6 | 1 | 79 | 357.821 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PYGL-1-E | Liver Glycogen Phosphorylase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1600 | 0.32 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PYGL_HUMAN | P06737 | Liver Glycogen Phosphorylase, Human | 1600 | 0.32 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Glycogen breakdown (glycogenolysis) |
