| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 24th, 2009 | 22 | Yes |
Popular Name: 5-chloro-N-[2-(cyclobutyl-methyl-amino)-2-oxo-ethyl]-1H-indole-2-carboxamide 5-chloro-N-[2-(cyclobutyl-methyl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.26 | 5.63 | -10.75 | 2 | 5 | 0 | 65 | 319.792 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PYGL-1-E | Liver Glycogen Phosphorylase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 170 | 0.43 | Binding ≤ 10μM |
| Z80477-1-O | SK_HEP1 (Hepatoma Cells) (cluster #1 Of 1), Other | Other | 1000 | 0.38 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PYGL_HUMAN | P06737 | Liver Glycogen Phosphorylase, Human | 170 | 0.43 | Binding ≤ 1μM |
| PYGL_HUMAN | P06737 | Liver Glycogen Phosphorylase, Human | 170 | 0.43 | Binding ≤ 10μM |
| Z80477 | Z80477 | SK_HEP1 (Hepatoma Cells) | 1000 | 0.38 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Glycogen breakdown (glycogenolysis) |
