UCSF

ZINC28349959

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Substance Information

In ZINC since Heavy atoms Benign functionality
February 26th, 2009 15 Yes

Popular Name: 5-amino-N-thiazol-2-yl-pyridine-2-carboxamide 5-amino-N-thiazol-2-yl-pyridine-…

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Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.37 1.29 -16.07 3 5 0 81 220.257 2 ↓
Hi High (pH 8-9.5) 0.43 0.1 -52.56 2 5 -1 87 219.249 2 ↓

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPM-2-B Methionine Aminopeptidase (cluster #2 Of 3), Bacterial Bacteria 2090 0.53 Binding ≤ 10μM
AMPM1-1-F Methionine Aminopeptidase 1 (cluster #1 Of 1), Fungal Fungi 2430 0.52 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
AMPM_ECOLI P0AE18 Methionine Aminopeptidase, Ecoli 2090 0.53 Binding ≤ 10μM
AMPM1_YEAST Q01662 Methionine Aminopeptidase 1, Yeast 2430 0.52 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Inactivation, recovery and regulation of the phototransduction cascade

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.