| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 26th, 2009 | 27 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.77 | 12.31 | -51.09 | 0 | 5 | -1 | 71 | 364.421 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PD2R-1-E | Prostanoid DP Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3900 | 0.28 | Binding ≤ 10μM |
| PE2R1-1-E | Prostanoid EP1 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 5200 | 0.27 | Binding ≤ 10μM |
| PE2R2-1-E | Prostanoid EP2 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2100 | 0.29 | Binding ≤ 10μM |
| PE2R3-1-E | Prostanoid EP3 Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 3300 | 0.28 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PD2R_MOUSE | P70263 | Prostanoid DP Receptor, Mouse | 10 | 0.41 | Binding ≤ 1μM |
| PD2R_MOUSE | P70263 | Prostanoid DP Receptor, Mouse | 10 | 0.41 | Binding ≤ 10μM |
| PE2R1_MOUSE | P35375 | Prostanoid EP1 Receptor, Mouse | 5200 | 0.27 | Binding ≤ 10μM |
| PE2R2_MOUSE | Q62053 | Prostanoid EP2 Receptor, Mouse | 2000 | 0.30 | Binding ≤ 10μM |
| PE2R3_MOUSE | P30557 | Prostanoid EP3 Receptor, Mouse | 3300 | 0.28 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Prostanoid ligand receptors |
