| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 26th, 2009 | 28 | Yes |
Popular Name: 2-[1-(4-butoxybenzoyl)-2,5-dimethyl-indol-3-yl]acetic 2-[1-(4-butoxybenzoyl)-2,5-dimet…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.19 | 12.97 | -55.49 | 0 | 5 | -1 | 71 | 378.448 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PD2R-1-E | Prostanoid DP Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2900 | 0.28 | Binding ≤ 10μM |
| PE2R1-1-E | Prostanoid EP1 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 5000 | 0.27 | Binding ≤ 10μM |
| PE2R2-1-E | Prostanoid EP2 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1700 | 0.29 | Binding ≤ 10μM |
| PE2R4-1-E | Prostanoid EP4 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2200 | 0.28 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PD2R_MOUSE | P70263 | Prostanoid DP Receptor, Mouse | 150 | 0.34 | Binding ≤ 1μM |
| PD2R_MOUSE | P70263 | Prostanoid DP Receptor, Mouse | 150 | 0.34 | Binding ≤ 10μM |
| PE2R1_MOUSE | P35375 | Prostanoid EP1 Receptor, Mouse | 5000 | 0.27 | Binding ≤ 10μM |
| PE2R2_MOUSE | Q62053 | Prostanoid EP2 Receptor, Mouse | 1700 | 0.29 | Binding ≤ 10μM |
| PE2R4_MOUSE | P32240 | Prostanoid EP4 Receptor, Mouse | 2200 | 0.28 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Prostanoid ligand receptors |
