In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
February 27th, 2009 | 17 | Yes |
Popular Name: DNC005076 DNC005076
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 3.72 | 6.24 | -10.62 | 2 | 3 | 0 | 48 | 230.311 | 5 | ↓ |
Lo Low (pH 4.5-6) | 3.72 | 6.75 | -27.8 | 3 | 3 | 1 | 49 | 231.319 | 5 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
MCHR1-2-E | Melanin-concentrating Hormone Receptor 1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 580 | 0.51 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
MCHR1_HUMAN | Q99705 | Melanin-concentrating Hormone Receptor 1, Human | 580 | 0.51 | Binding ≤ 1μM |
MCHR1_HUMAN | Q99705 | Melanin-concentrating Hormone Receptor 1, Human | 580 | 0.51 | Binding ≤ 10μM |
Description | Species |
---|---|
G alpha (i) signalling events | |
G alpha (q) signalling events | |
Peptide ligand-binding receptors |