| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 27th, 2009 | 17 | Yes |
Popular Name: 1,2,5-Oxadiazol-3-amine, 4-(3-ethyl-3H-imidazo[4,5-c]pyridin-2-yl)- (9CI) 1,2,5-Oxadiazol-3-amine, 4-(3-et…
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CAS Number: 607374-14-1
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.84 | 3.84 | -7.46 | 2 | 7 | 0 | 96 | 230.231 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KS6A5-1-E | Ribosomal Protein S6 Kinase Alpha 5 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1540 | 0.48 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KS6A5_HUMAN | O75582 | Ribosomal Protein S6 Kinase Alpha 5, Human | 1540 | 0.48 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| CREB phosphorylation | |
| ERK/MAPK targets | |
| NCAM signaling for neurite out-growth | |
| Recycling pathway of L1 |
No pre-computed analogs available. Try a structural similarity search.