In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
February 28th, 2009 | 24 | Yes |
Popular Name: 1-(benzenesulfonyl)-3-[[(2R)-pyrrolidin-2-yl]methyl]indole 1-(benzenesulfonyl)-3-[[(2R)-pyr…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 3.42 | 8.4 | -45.97 | 2 | 4 | 1 | 56 | 341.456 | 4 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
5HT6R-2-E | Serotonin 6 (5-HT6) Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 8 | 0.47 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
5HT6R_HUMAN | P50406 | Serotonin 6 (5-HT6) Receptor, Human | 7.8 | 0.47 | Binding ≤ 1μM |
5HT6R_HUMAN | P50406 | Serotonin 6 (5-HT6) Receptor, Human | 7.8 | 0.47 | Binding ≤ 10μM |
Description | Species |
---|---|
G alpha (s) signalling events | |
Serotonin receptors |