| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 28th, 2009 | 11 | Yes |
Popular Name: Spiro[2.3]hexane-1-carboxylic acid, 1-(aminomethyl)- (9CI) Spiro[2.3]hexane-1-carboxylic ac…
Find On: PubMed — Wikipedia — Google
CAS Number: 724773-02-8
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.70 | 2.5 | -47.44 | 3 | 3 | 0 | 68 | 155.197 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CA2D1-4-E | Voltage-gated Calcium Channel Alpha2/delta Subunit 1 (cluster #4 Of 4), Eukaryotic | Eukaryotes | 200 | 0.85 | Binding ≤ 10μM |
| CA2D2-1-E | Voltage-gated Calcium Channel Alpha2/delta Subunit 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 200 | 0.85 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CA2D1_HUMAN | P54289 | Voltage-gated Calcium Channel Alpha2/delta Subunit 1, Human | 200 | 0.85 | Binding ≤ 1μM |
| CA2D2_HUMAN | Q9NY47 | Voltage-gated Calcium Channel Alpha2/delta Subunit 2, Human | 200 | 0.85 | Binding ≤ 1μM |
| CA2D1_HUMAN | P54289 | Voltage-gated Calcium Channel Alpha2/delta Subunit 1, Human | 200 | 0.85 | Binding ≤ 10μM |
| CA2D2_HUMAN | Q9NY47 | Voltage-gated Calcium Channel Alpha2/delta Subunit 2, Human | 200 | 0.85 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Adrenaline,noradrenaline inhibits insulin secretion | |
| Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Chann | |
| Regulation of insulin secretion |
No pre-computed analogs available. Try a structural similarity search.