| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 6th, 2009 | 17 | Yes |
Popular Name: 2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxylic acid 2-phenyl-2,3-dihydro-1H-imidazo[…
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CAS Number: 946150-84-1
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.31 | 4.76 | -54.64 | 1 | 5 | -1 | 70 | 228.231 | 2 | ↓ |
| Mid Mid (pH 6-8) | 1.31 | 4.91 | -47.37 | 2 | 5 | 0 | 71 | 229.239 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FPR1-2-E | Formyl Peptide Receptor 1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 1 | 0.74 | Functional ≤ 10μM |
| FPR2-2-E | Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 1 | 0.74 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FPR1_HUMAN | P21462 | Formyl Peptide Receptor 1, Human | 1.16 | 0.74 | Functional ≤ 10μM |
| FPR2_HUMAN | P25090 | Lipoxin A4 Receptor, Human | 1.16 | 0.74 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Formyl peptide receptors bind formyl peptides and many other ligands | |
| G alpha (i) signalling events | |
| G alpha (q) signalling events |
No pre-computed analogs available. Try a structural similarity search.