UCSF

ZINC28711056

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
March 6th, 2009 19 Yes

Popular Name: N/A N/A

Find On: PubMed — Wikipedia — Google

CAS Number: 925705-73-3

Other Names:

TG 100713

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.71 0.91 -17.4 5 7 0 124 254.253 1 ↓
Lo Low (pH 4.5-6) 0.71 1.41 -33.08 6 7 1 125 255.261 1 ↓

Vendor Notes

Note Type Comments Provided By
Target PI3K Selleck Chemicals

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PK3CG-2-E PI3-kinase P110-gamma Subunit (cluster #2 Of 3), Eukaryotic Eukaryotes 40 0.55 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PK3CG_HUMAN P48736 PI3-kinase P110-gamma Subunit, Human 39.9 0.55 Binding ≤ 1μM
PK3CG_HUMAN P48736 PI3-kinase P110-gamma Subunit, Human 39.9 0.55 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
G beta:gamma signalling through PI3Kgamma
GPVI-mediated activation cascade
Synthesis of PIPs at the plasma membrane

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.