| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 6th, 2009 | 12 | No |
Popular Name: DNC013342 DNC013342
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -3.69 | -1.9 | -75.02 | 4 | 6 | -1 | 128 | 194.103 | 3 | ↓ |
| Mid Mid (pH 6-8) | -3.69 | -0.75 | -157.87 | 3 | 6 | -2 | 131 | 193.095 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4-2-E | Metabotropic Glutamate Receptor 4 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 7400 | 0.60 | Binding ≤ 10μM |
| GRM4-1-E | Metabotropic Glutamate Receptor 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 9400 | 0.59 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4_RAT | P31423 | Metabotropic Glutamate Receptor 4, Rat | 7400 | 0.60 | Binding ≤ 10μM |
| GRM4_RAT | P31423 | Metabotropic Glutamate Receptor 4, Rat | 9400 | 0.59 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events |
