| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 9th, 2009 | 28 | Yes |
Popular Name: IC87114 IC87114
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.06 | 5.3 | -12.88 | 1 | 5 | 0 | 51 | 379.456 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| JUN-1-E | Proto-oncogene C-JUN (cluster #1 Of 2), Eukaryotic | Eukaryotes | 110 | 0.35 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| JUN_HUMAN | P05412 | Proto-oncogene C-JUN, Human | 110 | 0.35 | Binding ≤ 1μM |
| JUN_HUMAN | P05412 | Proto-oncogene C-JUN, Human | 110 | 0.35 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of the AP-1 family of transcription factors | |
| FCERI mediated MAPK activation | |
| Oxidative Stress Induced Senescence | |
| Pre-NOTCH Transcription and Translation | |
| Senescence-Associated Secretory Phenotype (SASP) |
