| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 5th, 2004 | 23 | Yes |
Popular Name: [4-(4-chlorophenyl)thiazol-2-yl]-[3-(trifluoromethyl)phenyl]amine [4-(4-chlorophenyl)thiazol-2-yl]…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.21 | 1.95 | -7.67 | 1 | 2 | 0 | 24 | 354.784 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TERA-1-E | Transitional Endoplasmic Reticulum ATPase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8300 | 0.31 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TERA_HUMAN | P55072 | Transitional Endoplasmic Reticulum ATPase, Human | 8300 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Hedgehog ligand biogenesis | |
| Hh ligand biogenesis disease | |
| HSF1 activation |
