| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 10th, 2009 | 14 | Yes |
Popular Name: 2-(naphthalen-1-yl)cyclopropan-1-amine hydrochloride 2-(naphthalen-1-yl)cyclopropan-1…
Find On: PubMed — Wikipedia — Google
CAS Numbers: 1203-44-7 , 1820569-12-7 , 944-64-9
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.58 | 6.02 | -49.27 | 3 | 1 | 1 | 28 | 184.262 | 1 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KDM1A-1-E | Lysine-specific Histone Demethylase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8000 | 0.51 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KDM1A_HUMAN | O60341 | Lysine-specific Histone Demethylase 1, Human | 8000 | 0.51 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Factors involved in megakaryocyte development and platelet production | |
| HDACs deacetylate histones | |
| HDMs demethylate histones |
