| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 10th, 2009 | 35 | Yes |
Popular Name: 2-[4-(2-dimethylaminoethyl)anilino]-8-indan-5-yl-5-oxo-pyrido[2,3-d]pyrimidine-6-carboxamide 2-[4-(2-dimethylaminoethyl)anili…
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| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.36 | 15.71 | -57.4 | 4 | 8 | 1 | 107 | 469.569 | 7 | ↓ |
| Hi High (pH 8-9.5) | 2.36 | 13.18 | -23.2 | 3 | 8 | 0 | 106 | 468.561 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CSF1R-1-E | Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 3 | 0.34 | Binding ≤ 1μM |
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 3 | 0.34 | Binding ≤ 10μM |
