| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 10th, 2009 | 38 | Yes |
Popular Name: 8-indan-5-yl-2-[4-(2-morpholinoethyl)anilino]-5-oxo-pyrido[2,3-d]pyrimidine-6-carboxamide 8-indan-5-yl-2-[4-(2-morpholinoe…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.21 | 12.81 | -24.51 | 3 | 9 | 0 | 115 | 510.598 | 7 | ↓ |
| Mid Mid (pH 6-8) | 2.21 | 15.15 | -60.26 | 4 | 9 | 1 | 117 | 511.606 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CSF1R-1-E | Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8 | 0.30 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 8 | 0.30 | Binding ≤ 1μM |
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 8 | 0.30 | Binding ≤ 10μM |
