| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 10th, 2009 | 32 | Yes |
Popular Name: 2-(3-imidazol-1-ylpropylamino)-8-indan-5-yl-5-oxo-pyrido[2,3-d]pyrimidine-6-carboxamide 2-(3-imidazol-1-ylpropylamino)-8…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.39 | 13.01 | -27.81 | 3 | 9 | 0 | 121 | 429.484 | 7 | ↓ |
| Mid Mid (pH 6-8) | 0.39 | 13.49 | -56.59 | 4 | 9 | 1 | 122 | 430.492 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CSF1R-1-E | Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2300 | 0.25 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 2300 | 0.25 | Binding ≤ 10μM |
