| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 10th, 2009 | 27 | No |
Popular Name: N-[(4-benzyloxyphenyl)methyleneamino]-3-chloro-4-hydroxy-benzamide N-[(4-benzyloxyphenyl)methylenea…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.14 | 8.02 | -18.13 | 2 | 5 | 0 | 71 | 380.831 | 6 | ↓ |
| Hi High (pH 8-9.5) | 5.14 | 8.69 | -48.42 | 1 | 5 | -1 | 74 | 379.823 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PACR-1-E | Pituitary Adenylate Cyclase-activating Polypeptide Type I Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 522 | 0.33 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PACR_HUMAN | P41586 | Pituitary Adenylate Cyclase-activating Polypeptide Type I Receptor, Human | 522 | 0.33 | Binding ≤ 1μM |
| PACR_HUMAN | P41586 | Pituitary Adenylate Cyclase-activating Polypeptide Type I Receptor, Human | 522 | 0.33 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (s) signalling events | |
| Glucagon-type ligand receptors | |
| NGF-independant TRKA activation |
