| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 11th, 2009 | 33 | Yes |
Popular Name: [(Z)-2-(4-butylphenyl)vinyl]-(2-chlorophenyl)-methyl-BLAH [(Z)-2-(4-butylphenyl)vinyl]-(2-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.72 | 15.94 | -13.45 | 0 | 4 | 0 | 43 | 473.045 | 6 | ↓ |
| Mid Mid (pH 6-8) | 6.72 | 16.83 | -35.35 | 1 | 4 | 1 | 45 | 474.053 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PTAFR-2-E | Platelet Activating Factor Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 10 | 0.34 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PTAFR_HUMAN | P25105 | Platelet Activating Factor Receptor, Human | 10 | 0.34 | Binding ≤ 1μM |
| PTAFR_HUMAN | P25105 | Platelet Activating Factor Receptor, Human | 10 | 0.34 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | |
| G alpha (q) signalling events | |
| Interferon gamma signaling |
