| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 21 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.43 | 0.8 | -18.45 | 1 | 6 | 0 | 84 | 306.705 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TAAR1-1-E | Trace Amine-associated Receptor 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 37 | 0.50 | Binding ≤ 10μM |
| TAAR1-1-E | Trace Amine-associated Receptor 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 12 | 0.53 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TAAR1_MOUSE | Q923Y8 | Trace Amine-associated Receptor1, Mouse | 37 | 0.50 | Binding ≤ 1μM |
| TAAR1_MOUSE | Q923Y8 | Trace Amine-associated Receptor1, Mouse | 37 | 0.50 | Binding ≤ 10μM |
| TAAR1_MOUSE | Q923Y8 | Trace Amine-associated Receptor1, Mouse | 12 | 0.53 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Amine ligand-binding receptors | |
| G alpha (s) signalling events |
