| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 21 | No |
Popular Name: 2-amino-4-methyl-5-oxo-7-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 2-amino-4-methyl-5-oxo-7-phenyl-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.67 | 6.2 | -11.73 | 2 | 4 | 0 | 76 | 280.327 | 1 | ↓ |
| Lo Low (pH 4.5-6) | 2.67 | 6.58 | -53.84 | 3 | 4 | 1 | 78 | 281.335 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EAA1-1-E | Excitatory Amino Acid Transporter 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 9200 | 0.34 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EAA1_HUMAN | P43003 | Excitatory Amino Acid Transporter 1, Human | 9120.10839 | 0.34 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | |
| Transport of inorganic cations/anions and amino acids/oligopeptides |
