| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 7th, 2009 | 24 | No |
Popular Name: (5Z)-2-(3-chloroanilino)-5-[(Z)-2-methyl-3-phenyl-prop-2-enylidene]thiazol-4-one (5Z)-2-(3-chloroanilino)-5-[(Z)-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.11 | 10.23 | -43.77 | 0 | 3 | -1 | 44 | 353.854 | 4 | ↓ |
| Mid Mid (pH 6-8) | 6.11 | 10.65 | -19.18 | 1 | 3 | 0 | 42 | 354.862 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MPIP2-1-E | Dual Specificity Phosphatase Cdc25B (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3300 | 0.32 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MPIP2_HUMAN | P30305 | Dual Specificity Phosphatase Cdc25B, Human | 3300 | 0.32 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Cyclin A/B1 associated events during G2/M transition | |
| Cyclin A:Cdk2-associated events at S phase entry | |
| Cyclin B2 mediated events |
