UCSF

ZINC34635728

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
September 17th, 2009 24 No

Popular Name: DNC011218 DNC011218

Find On: PubMed — Wikipedia — Google

Other Names:

PONKORANOL

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
LYAG-2-E Alpha-glucosidase (cluster #2 Of 2), Eukaryotic Eukaryotes 3200 0.32 Binding ≤ 10μM
MGA-2-E Maltase-glucoamylase (cluster #2 Of 3), Eukaryotic Eukaryotes 170 0.39 Binding ≤ 10μM
SUIS-2-E Sucrase-isomaltase (cluster #2 Of 3), Eukaryotic Eukaryotes 290 0.38 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
MGA_HUMAN O43451 Maltase-glucoamylase, Human 170 0.39 Binding ≤ 1μM
SUIS_RAT P23739 Sucrase-isomaltase, Rat 290 0.38 Binding ≤ 1μM
LYAG_RAT Q6P7A9 Acidic Alpha-glucosidase, Rat 3200 0.32 Binding ≤ 10μM
MGA_HUMAN O43451 Maltase-glucoamylase, Human 170 0.39 Binding ≤ 10μM
SUIS_RAT P23739 Sucrase-isomaltase, Rat 2600 0.33 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Digestion of dietary carbohydrate

Analogs ( Draw Identity 99% 90% 80% 70% )