| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 24th, 2009 | 32 | No |
Popular Name: 4-[(E)-3-[8,8-dimethyl-5-(p-tolyl)-7H-naphthalen-2-yl]-3-oxo-prop-1-enyl]benzoic 4-[(E)-3-[8,8-dimethyl-5-(p-toly…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 7.21 | 17.32 | -50.99 | 0 | 3 | -1 | 57 | 421.516 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| RARA-1-E | Retinoic Acid Receptor Alpha (cluster #1 Of 1), Eukaryotic | Eukaryotes | 300 | 0.29 | Binding ≤ 10μM |
| RARB-1-E | Retinoic Acid Receptor Beta (cluster #1 Of 2), Eukaryotic | Eukaryotes | 400 | 0.28 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| RARA_MOUSE | P11416 | Retinoic Acid Receptor Alpha, Mouse | 300 | 0.29 | Binding ≤ 1μM |
| RARB_MOUSE | P22605 | Retinoic Acid Receptor Beta, Mouse | 400 | 0.28 | Binding ≤ 1μM |
| RARA_MOUSE | P11416 | Retinoic Acid Receptor Alpha, Mouse | 300 | 0.29 | Binding ≤ 10μM |
| RARB_MOUSE | P22605 | Retinoic Acid Receptor Beta, Mouse | 400 | 0.28 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Nuclear Receptor transcription pathway |
