| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 25th, 2009 | 35 | Yes |
Popular Name: N-[[4-[[4-(4-chloroanilino)quinazolin-2-yl]amino]cyclohexyl]methyl]benzamide N-[[4-[[4-(4-chloroanilino)quina…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 7.05 | 15.45 | -15.75 | 3 | 6 | 0 | 79 | 486.019 | 7 | ↓ |
| Mid Mid (pH 6-8) | 7.05 | 15.79 | -35.49 | 4 | 6 | 1 | 80 | 487.027 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NPY5R-1-E | Neuropeptide Y Receptor Type 5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 310 | 0.26 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NPY5R_HUMAN | Q15761 | Neuropeptide Y Receptor Type 5, Human | 310 | 0.26 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Peptide ligand-binding receptors |
