In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
September 29th, 2009 | 34 | Yes |
Popular Name: N-[4-(4-benzyl-1-piperidyl)-3-(piperidine-1-carbonyl)phenyl]-2,2-dimethyl-propanamide N-[4-(4-benzyl-1-piperidyl)-3-(p…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.30 | 14.68 | -9.99 | 1 | 5 | 0 | 53 | 461.65 | 6 | ↓ |
Popular Name: 1-[3-(4-benzoylpiperidine-1-carbonyl)phenyl]pyrrolidin-2-one 1-[3-(4-benzoylpiperidine-1-carb…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.16 | 10.88 | -27.28 | 0 | 5 | 0 | 58 | 376.456 | 4 | ↓ |
Popular Name: N-[2-(4-benzylpiperidine-1-carbonyl)phenyl]-N-methyl-cyclopropanecarboxamide N-[2-(4-benzylpiperidine-1-carbo…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 3.73 | 13.19 | -17.68 | 0 | 4 | 0 | 41 | 376.5 | 5 | ↓ |
Popular Name: N-[3-(4-benzylpiperidine-1-carbonyl)phenyl]propanamide N-[3-(4-benzylpiperidine-1-carbo…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 3.51 | 10.34 | -15.5 | 1 | 4 | 0 | 49 | 350.462 | 5 | ↓ |
Popular Name: 1-[3-[(4-benzyl-1-piperidyl)carbonyl]phenyl]pyrrolidin-2-one 1-[3-[(4-benzyl-1-piperidyl)carb…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.82 | 0.63 | -20.89 | 0 | 4 | 0 | 40 | 362.473 | 4 | ↓ |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 3.76 | 0.4 | -12.13 | 1 | 4 | 0 | 49 | 364.489 | 5 | ↓ |