UCSF

ZINC34836571

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Substance Information

In ZINC since Heavy atoms Benign functionality
September 29th, 2009 27 Yes

Popular Name: N-(m-tolyl)-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide N-(m-tolyl)-4-(3-phenyl-1,2,4-th…

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Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.34 10.57 -13.81 1 6 0 61 379.489 3 ↓

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
FAAH1-1-E Anandamide Amidohydrolase (cluster #1 Of 7), Eukaryotic Eukaryotes 148 0.35 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
FAAH1_RAT P97612 Anandamide Amidohydrolase, Rat 148 0.35 Binding ≤ 1μM
FAAH1_HUMAN O00519 Anandamide Amidohydrolase, Human 193 0.35 Binding ≤ 1μM
FAAH1_RAT P97612 Anandamide Amidohydrolase, Rat 148 0.35 Binding ≤ 10μM
FAAH1_HUMAN O00519 Anandamide Amidohydrolase, Human 193 0.35 Binding ≤ 10μM

Analogs ( Draw Identity 99% 90% 80% 70% )