In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 14th, 2009 | 36 | Yes |
Popular Name: ethyl ethyl
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.67 | 14.77 | -52.01 | 0 | 9 | -1 | 102 | 502.986 | 10 | ↓ |
Lo Low (pH 4.5-6) | 5.67 | 14.85 | -18.98 | 1 | 9 | 0 | 104 | 503.994 | 10 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
AGTRB-1-E | Angiotensin II Type 1b (AT-1b) Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 25 | 0.30 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
AGTRB_RAT | P29089 | Angiotensin II Type 1b (AT-1b) Receptor, Rat | 25 | 0.30 | Binding ≤ 1μM |
AGTRB_RAT | P29089 | Angiotensin II Type 1b (AT-1b) Receptor, Rat | 25 | 0.30 | Binding ≤ 10μM |
Description | Species |
---|---|
G alpha (q) signalling events | |
Peptide ligand-binding receptors |