| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 23rd, 2009 | 28 | Yes |
Popular Name: N-benzyl-2-[(1S)-3-(2-methoxyethyl)-2-oxo-1H-imidazo[1,2-a]benzimidazol-1-yl]acetamide N-benzyl-2-[(1S)-3-(2-methoxyeth…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.85 | 10.91 | -13.88 | 1 | 7 | 0 | 76 | 378.432 | 7 | ↓ |
| Mid Mid (pH 6-8) | 1.85 | 11.38 | -30.8 | 2 | 7 | 1 | 78 | 379.44 | 7 | ↓ |
Popular Name: N-benzyl-2-[(1R)-3-(3-methoxypropyl)-2-oxo-1H-imidazo[1,2-a]benzimidazol-1-yl]acetamide N-benzyl-2-[(1R)-3-(3-methoxypro…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.12 | 11.79 | -14.42 | 1 | 7 | 0 | 76 | 392.459 | 8 | ↓ |
| Mid Mid (pH 6-8) | 2.12 | 12.26 | -35.84 | 2 | 7 | 1 | 78 | 393.467 | 8 | ↓ |
Popular Name: N-benzyl-2-[(1S)-3-(3-methoxypropyl)-2-oxo-1H-imidazo[1,2-a]benzimidazol-1-yl]acetamide N-benzyl-2-[(1S)-3-(3-methoxypro…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.12 | 11.79 | -13.9 | 1 | 7 | 0 | 76 | 392.459 | 8 | ↓ |
| Mid Mid (pH 6-8) | 2.12 | 12.26 | -35.25 | 2 | 7 | 1 | 78 | 393.467 | 8 | ↓ |
Popular Name: N-benzyl-2-[(1R)-3-(3-morpholinopropyl)-2-oxo-1H-imidazo[1,2-a]benzimidazol-1-yl]acetamide N-benzyl-2-[(1R)-3-(3-morpholino…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.01 | 11.26 | -14.18 | 1 | 8 | 0 | 80 | 447.539 | 8 | ↓ |
| Mid Mid (pH 6-8) | 2.01 | 13.53 | -42.96 | 2 | 8 | 1 | 81 | 448.547 | 8 | ↓ |
| Mid Mid (pH 6-8) | 2.01 | 11.73 | -36.89 | 2 | 8 | 1 | 81 | 448.547 | 8 | ↓ |
Popular Name: N-benzyl-2-[(1S)-3-(3-morpholinopropyl)-2-oxo-1H-imidazo[1,2-a]benzimidazol-1-yl]acetamide N-benzyl-2-[(1S)-3-(3-morpholino…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.01 | 11.26 | -13.99 | 1 | 8 | 0 | 80 | 447.539 | 8 | ↓ |
| Mid Mid (pH 6-8) | 2.01 | 13.53 | -44.54 | 2 | 8 | 1 | 81 | 448.547 | 8 | ↓ |
| Mid Mid (pH 6-8) | 2.01 | 11.73 | -36.71 | 2 | 8 | 1 | 81 | 448.547 | 8 | ↓ |
![1,3-dihydroimidazo[1,2-a]benzimidazol-2-one](http://zinc12.docking.org/img/rings/12321.gif)
![N-benzyl-2-(2-keto-1,3-dihydroimidazo[1,2-a]benzimidazol-1-yl)acetamide](http://zinc12.docking.org/img/rings/61357.gif)
