In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 23rd, 2009 | 38 | No |
Popular Name: benzyl benzyl
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 4.64 | 7.85 | -61.49 | 6 | 9 | 1 | 141 | 525.67 | 17 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
PLMN-2-E | Plasminogen (cluster #2 Of 2), Eukaryotic | Eukaryotes | 8900 | 0.19 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
PLMN_RAT | Q01177 | Plasminogen, Rat | 8900 | 0.19 | Binding ≤ 10μM |
Description | Species |
---|---|
Activation of Matrix Metalloproteinases | |
Degradation of the extracellular matrix | |
Dissolution of Fibrin Clot | |
Platelet degranulation | |
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l | |
Signaling by PDGF |