| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 24th, 2009 | 36 | Yes |
Popular Name: 4-[3-[(2R)-2-[(3R)-3-hydroxy-4-(3-phenoxyphenyl)butyl]-5-oxo-pyrrolidin-1-yl]propyl]benzoic 4-[3-[(2R)-2-[(3R)-3-hydroxy-4-(…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.72 | 14.62 | -62.7 | 1 | 6 | -1 | 90 | 486.588 | 12 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R4-1-E | Prostanoid EP4 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 220 | 0.26 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R4_RAT | P43114 | Prostanoid EP4 Receptor, Rat | 220 | 0.26 | Binding ≤ 1μM |
| PE2R4_RAT | P43114 | Prostanoid EP4 Receptor, Rat | 220 | 0.26 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (s) signalling events | |
| Prostanoid ligand receptors |
![5-[4-(3-phenoxyphenyl)butyl]-1-(3-phenylpropyl)-2-pyrrolidone](http://zinc12.docking.org/img/rings/77771.gif)
